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Harrow secures global rights to dry eye nasal spray TYRVAYA in milestone deal

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Harrow secures global rights to dry eye nasal spray TYRVAYA in milestone deal
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Ophthalmic pharmaceutical firm Harrow has completed its acquisition of global commercial rights to TYRVAYA nasal spray from Viatris, strengthening its ocular surface portfolio and expanding market reach across North America and key international markets.

UNITED STATES OF AMERICA —Harrow, a North American ophthalmic disease management company, has completed the purchase of worldwide rights to the dry eye treatment TYRVAYA from Viatris, excluding Japan, where Viatris retains commercialization rights in exchange for future royalty payments to Harrow.

Under the financial terms, Harrow paid $30 million in upfront cash from existing funds, with potential contingent milestone payments tied to future net sales bringing the total transaction value up to $100 million. TYRVAYA, a cholinergic agonist delivered via nasal spray, is the first FDA-approved non-topical treatment designed to stimulate natural tear production. The medication currently holds regulatory approval in the U.S., China, and Taiwan, with additional global filings under review.

This transaction significantly strengthens Harrow’s position in the ophthalmic pharmaceutical market by expanding its dry eye franchise alongside its flagship prescription therapy VEVYE. By integrating TYRVAYA’s established prescriber base and onboarding approximately 40 commercial personnel from Viatris, Harrow scales its market penetration and operational infrastructure across specialty pharmacy channels and distribution networks in North America.

For healthcare decision-makers and investors, the move demonstrates a strategic shift toward offering diversified treatment modalities for chronic ocular conditions. The integration leverages shared commercial platforms to drive revenue efficiencies, with commercial contributions expected to accelerate in 2027 and bolster long-term market access in the growing dry eye therapeutics sector.

Harrow, Inc. is a Nasdaq-listed pharmaceutical company focused on the development and commercialization of ophthalmic therapies across North America. Viatris Inc. is a global healthcare company specializing in branded, generic, and specialty pharmaceuticals across multiple therapeutic areas.

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